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Writer's pictureThe Big Magazine Staff

Trailer: Demi Moore, Margaret Qualley and Dennis Quaid Star in 'The Substance' Coralie Fargeat’s New Body-Horror Film

By The Big Magazine Staff


Demi Moore is generating early Oscar buzz for her role in Coralie Fargeat’s new thriller, The Substance, about a woman who sets out on a dangerous path for youth and beauty.


Watch The Substance Trailer: Demi Moore, Margaret Qualley and Dennis Quaid



Moore plays aging celebrity Elizabeth Sparkle who has just been fired from a TV show by her crude boss (Dennis Quaid) who tells her women over 50 are disposable. She decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.


“The Substance” debuted and received acclaim at the 2024 Cannes Film Festival, earning an enthusiastic 11-minute standing ovation.


The official synopsis reads:

Have you ever dreamt of a better version of yourself?
You. Only better in every way.
You should try this new product, The Substance.
IT CHANGED MY LIFE.

The movie features Margaret Qualley, Demi Moore, and Dennis Quaid, and is written and directed by Coralie Fargeat, the French filmmaker known for the 2017 TIFF film Revenge, starring Matilda Anna Ingrid Lutz.


Mubi has obtained the rights to distribute the movie in North America, and plans to exclusively screen it in theaters.


“The Substance” will open nationwide on Sept. 20.


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